徐辉,博士,副教授,硕士生导师
联系方式:xuhui_scu@scu.edu.cn 办公室电话:+86-028-85469573
招生方向:1、生物学——微生物学;2、生物学——生物信息学;
学习和工作简历
1996-2000 四川大学生物工程系 学士
2003-2006 四川大学生命科学学院 硕士
2009-2012 四川大学生命科学学院 博士
曾在制药公司从事6年生物医药研发工作。2012年至今,到四川大学生命科学学院从事教学科研工作,先后担任讲师、副教授。
主讲课程
《发酵工程》 (本科生)
《生物制品学》 (本科生)
《工业微生物》 (研究生)
研究方向:微生物生理代谢工程与比较基因组学
长期从事1)重要模式及工业微生物的生理与代谢功能的调控机制、生物合成与生理适应能力的重构及优化等研究,解析代谢产物生成的分子基础和调控机制,改造和优化重要工业微生物的生理和代谢功能,提升代谢产物的生产水平,实现低成本生物制造;2)开展盐藻等光合微生物的代谢工程与合成生物学研究,建立萜类化合物的光合自养细胞工厂。
主持的科研项目
1、国家自然科学基金面上项目(2016-2020)
2、成都市科技局科技创新项目(2020-2021)
3、四川省应用基础项目(2019-2021)
4、四川大学创新“火花库”项目(2019-2021)
5、四川省科技厅支撑项目(2014-2017)
6、国际合作项目(2013-2015)
发表文章(*为通讯作者,#为共同第一作者)
Bu C, Zhang Q, Zeng J, Cao X, Hao Z, Qiao D, Cao Y*, Xu H*, Identification of a novel anthocyanin synthesis pathway in the fungus Aspergillus sydowii H-1, BMC Genomics. 21(1) (2020) 29.
Tang Z, Cao X, Zhang Y, Jiang J, Qiao D, Xu H* and Cao Y*, Two splice variants of the DsMEK1 mitogen-activated protein kinase kinase (MAPKK) are involved in salt stress regulation in Dunaliella salina in different ways, Biotechnology for Biofuels, 13(2020):147
Tang Z, Cao X, Qiao J, Huang G, Lian, W, Qiao D, Xu H*, Cao Y*, MAPKKK gene family in Dunaliella salina: identification, interaction network, and expression patterns under abiotic stress, 32 (1) (2020) 243-253
H. Xu, N. Zhao, H. Yao, H. Qin, J. Zeng, Y. Ran, Y. Yang, D. Qiao, Y. Cao*, Lipid production from corn stover by a cost-efficient system featuring ammonium carbonate-steam explosion and recirculating enzymatic hydrolysis, Biomass and Bioenergy 120 (2019) 387-395.
T. Cai, H. Wu, J. Qin, J. Qiao, Y. Yang, Y. Wu, D. Qiao, H. Xu*, Y. Cao*, In vitro evaluation by PCA and AHP of potential antidiabetic properties of lactic acid bacteria isolated from traditional fermented food, LWT-Food Science and Technology 115 (2019) 108455.
Q. Wu, Y. Lan, X. Cao, H. Yao, D. Qiao, H. Xu*, Y. Cao*, Characterization and diverse evolution patterns of glycerol-3-phosphate dehydrogenase family genes in Dunaliella salina, Gene 710 (2019) 161-169.
H. Xu#, Y. Cao#, X. Li, X. Cao, Y. Xu, D. Qiao, Y. Cao*, An electrospun chitosan-based nanofibrous membrane reactor immobilized by the non-glycosylated rPGA for hydrolysis of pectin-rich biomass, Renewable Energy 126 (2018) 573-582.
W. Zhang#, H. Xu#, Y. Wu, J. Zeng, Z. Guo, L. Wang, C. Shen, D. Qiao, Y. Cao, A new cold-adapted, alkali-stable and highly salt-tolerant esterase from Bacillus licheniformis, Int J Biol Macromol 111 (2018) 1183-1193.
H. Xu#, S. Qin#, Y. Lan, M. Liu, X. Cao, D. Qiao, Y. Cao, Y. Cao*, Comparative genomic analysis of Paenibacillus sp. SSG-1 and its closely related strains reveals the effect of glycometabolism on environmental adaptation, Sci Rep 7(1) (2017) 5720.
T. Song#, H. Xu#, C. Wei, T. Jiang, S. Qin, W. Zhang, Y. Cao, C. Hu, F. Zhang, D. Qiao, Y. Cao, Horizontal Transfer of a Novel Soil Agarase Gene from Marine Bacteria to Soil Bacteria via Human Microbiota, Sci Rep 6 (2016) 34103.
H. Zhou, X. Li, M. Guo, Q. Xu, Y. Cao, D. Qiao, Y. Cao, H. Xu*, Secretory Expression and Characterization of an Acidic Endo-Polygalacturonase Gene from Aspergillus niger SC323 in Saccharomyces cerevisiae, J Microbiol Biotechnol 25(7) (2015) 999-1006.
专利及获奖
2020年第5届全国大学生生命科学创新创业大赛,全国一等奖,指导教师;
2018年四川省第五届“生命之星”科技邀请赛优秀指导教师;
获国家发明专利3项:ZL201510507610.5,ZL201310080376.3,ZL201210013396.4;