个人简介

周华鹏，博士，教授，博士生导师，四川省第十三批学术和技术带头人后备人选。长期从事植物逆境生物学研究，着重解析植物感受环境胁迫过程中所发生的遗传和分子特性的变化，以期寻找植物抗逆性的关键调节基因，阐明植物响应逆境胁迫的信号调控网络并鉴定可提高植物适应逆境的关键作用元件，探究植物对逆境胁迫的应答与耐受机理，为遗传改良作物提供科学依据与潜在基因资源。

主讲课程

《植物逆境分子生物学》（本科生）

《微观生物学》（硕士研究生）

《生物安全研究进展》（博士研究生）

研究成果

以模式植物拟南芥等为研究对象，发现了去泛素化酶（UBP）家族成员介导的蛋白质去泛素化修饰过程对植物耐盐抗旱性及脱落酸信号途径等具有重要调节作用；阐明了通用调节因子（GRF）14-3-3蛋白参与调节植物耐盐性的分子机制；解析了GSK3类蛋白激酶BIN2通过SOS2而调节植物耐盐性的分子机制；阐明了转录因子MYB30通过转录调节交替氧化酶AOX1a而影响盐胁迫下植物体内的氧化还原平衡以提高植物耐盐性的分子机制；解析了蛋白激酶SIMP1通过蛋白酶体成熟因子UMP1A影响蛋白酶体成熟过程而提高ERAD效率，从而缓解内质网胁迫而提高植物耐盐能力的分子机制；阐明了PIP3小肽通过类受体激酶RLK7激活MPK3/6而提高植物对盐胁迫的应答与耐受能力的信号网络。相关研究成果先后发表于Developmental Cell（2020年）、Plant Cell（2012年、2014年、2021年）、New Phytologist（2020年、2021年）、Plant Cell and Environment（2016年）及Plant Journal（2020年、2021年）等国际权威期刊上，先后被Cell、Trends in Plant Science等国际顶级综述文章引用介绍，截止目前他引次数大于900次。上述成果为进一步理解植物的抗逆性等提供了新的证据，对于遗传改良作物、提高其抗逆能力等具有重要的科学指导意义。

研究方向

通过正向/反向遗传学手段筛选鉴定调节植物应对盐害、干旱等逆境胁迫新的调节因子与调控原件，解析植物对逆境胁迫的应答与耐受过程的信号调控网络，为遗传改良作物提供新的基因资源与遗传靶标。

招生方向

1、生物学-植物学（硕士/博士）

2、生物学-生物化学与分子生物学（硕士/博士）

联系方式

工作邮箱：zhouhuapeng@scu.edu.cn

学术主页

https://www.researchgate.net/profile/Huapeng_Zhou

主持项目

1、国家自然科学基金青年科学基金项目（2016年）

2、国家自然科学基金面上项目（2018年）

3、四川大学创新“火花库”项目（2019年）

4、山东师范大学逆境植物重点实验室开放课题项目（2020年）

5、四川大学青年科技学术带头人培育项目（2020年）

6、国家自然科学基金面上项目（2021年）

研究论文

(注：#,第一作者；*，通讯作者)

28、Fei Xiao and Huapeng Zhou^(*). (2023). Plant salt response: Perception, signaling, and tolerance. Frontiers in Plant Science, doi: 0.3389/fpls.2022.1053699. [通讯作者]

27、Kaili Nie, Hongyun Zhao, Xiaopei Wang, Yanli Niu, Huapeng Zhou^(*) and Yuan Zheng^(*). (2022). The MIEL1-ABI5/MYB30 regulatory module fine tunes abscisic acid signaling during seed germination. Journal of Integrative Plant Biology, 64:930-941. [通讯作者]

26、Huapeng Zhou^(*)(#), Fei Xiao^(#), Yuan Zheng^(#), Guoyong Liu, Yufen Zhuang, Zhiyue Wang, Yiyi Zhang, Jiaxian He, Chunxiang Fu and Honghui Lin^(*). (2022). PAMP-INDUCED SECRETED PEPTIDE3 modulates salt tolerance through RECEPTOR-LIKE KINASE7 in plants. Plant Cell, 34:927-944. [第一作者/通讯作者]

25、Ruijuan Yang, Zhenying Wu, Chen Bai, Zhichao Sun, Mengqi Wang, Yuzhu Huo, Hailing Zhang, Yamei Wang, Huapeng Zhou, Shaojun Dai, Wenwen Liu^(*) and Chunxiang Fu^(*). (2021). Overexpression of PvWOX3a in switchgrass promotes stem development and increases plant height. Horticulture Research, 8:252.

24、Jiaxian He^(#), Yufen Zhuang^(#), Chuan Li, Xia Sun, Shuangshuang Zhao, Changle Ma, Honghui Lin^(*), Huapeng Zhou^(*).(2021).SIMP1 modulates salt tolerance by elevating ERAD efficiency through UMP1A-mediated proteasome maturation in plants. New Phytologist, 232:625-641. [通讯作者]

23、Shuangshuang Zhao^(*), Qikun Zhang, Mingyue Liu, Huapeng Zhou, Changle Ma, Pingping Wang^(*). (2021). Regulation of Plant Responses to Salt Stress. International Journal of Molecular Sciences, 22(9):4609. doi.org/10.3390/ijms22094609.

22、Fei Xiao^(#), Yiyi Zhang^(#), Shuangshuang Zhao, Huapeng Zhou^(*).(2021). MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis. Plant Signaling & Behavior, doi: 10.1080/15592324.2021.1913310.[通讯作者]

21、Xia Sun^(#), Qiongqiong Zhang^(#), Huapeng Zhou^(*).(2021). Anthocyanins: from biosynthesis regulation to crop improvement. Botany Letters, doi: 10.1080/23818107.2021.1909498.[通讯作者]

20、Fei Xiao^(#), Qianyuan Gong^(#), Shuangshuang Zhao, Honghui Lin^(*), Huapeng Zhou^(*).(2021). MYB30 and ETHYLENE INSENSITIVE3 Antagonistically Modulate Root Hair Growth in Arabidopsis. Plant Journal, 106: 480-492.[通讯作者]

19、Fei Xiao^(#), Xiaochuan Li^(#),Jiaxian He^(#) Jinfeng Zhao, Guochun Wu, Qianyuan Gong, Huapeng Zhou^(*), Honghui Lin^(*).(2021). Protein kinase PpCIPK1 modulates plant salt tolerance in Physcomitrella patens. Plant Molecular Biology, 105: 685-696.[通讯作者]

18、Jianfang Li^(#), Huapeng Zhou^(#), Yan Zhang, Zhen Li, Yongqing Yang, Yan Guo^(*).(2020). The GSK3-like kinase BIN2 is a molecular switch between the salt stress response and growth recovery in Arabidopsis thaliana. Developmental Cell, 55(3):367-380.[第一作者]

17、Hongyun Zhao^(#), Kaili Nie^(#), Huapeng Zhou^(#), Xiaojing Yan, Qidi Zhan, Yuan Zheng^(*), Chun-peng Song.(2020). ABI5 modulates seed germination via feedback regulation of the expression of the PYR/PYL/RCAR ABA receptor genes. New Phytologist, 228(2):596-608.[第一作者]

16、Yunhong Liu^(#), Qianyuan Gong^(#), Jiaxian He, Xia Sun, Xiaochuan Li, Shuangshuang Zhao, Qingwei Meng, Honghui Lin, Huapeng Zhou^(*). (2020). PpAOX regulates ER stress tolerance in Physcomitrella patens. Journal of Plant Physiology, 251:153218.[通讯作者]

15、Qianyuan Gong^(#)，Sha Li^(#), Yuan Zheng^(#), Hongqin Duan^(#), Fei Xiao, Yufen Zhuang, Jiaxian He, Guochun Wu, Shuangshuang Zhao, Huapeng Zhou^(*), Honghui Lin^(*). (2020). SUMOylation of MYB30 enhances salt tolerance by elevating alternative respiration via transcriptionally upregulating AOX1a in Arabidopsis. Plant Journal, 102:1157-1171.[通讯作者]

14、Xia Sun, Yufen Zhuang, Honghui Lin, Huapeng Zhou^(*). (2019). Patellin1 negatively regulates plant salt tolerance by attenuating nitric oxide accumulation in Arabidopsis. Plant Signaling & Behavior, 14(12):1-4.[通讯作者]

13、Guochun Wu^(#), Sha Li^(#), Xiaochuan Li, Yunhong Liu, Shuangshuang Zhao, Baohui Liu, Huapeng Zhou^(*),Honghui Lin^(*).(2019). A functional alternative oxidase modulates plant salt tolerance in Physcomitrella patens. Plant and Cell Physiology, 60(8):1829-1841.[通讯作者]

12、Huapeng Zhou^(*), Hongqin Duan, Yunhong Liu, Xia Sun, Jinfeng Zhao, Honghui Lin^(*). (2019). Patellin protein family functions in plant development and stress response. Journal of Plant Physiology, 234-234:94-97.[第一作者/通讯作者]

11、Huapeng Zhou^(*), Chongwu Wang, Tinghong Tan, Jingqing Cai, Jiaxian He, Honghui Lin^(*). (2018). Patellin1 negatively modulates salt tolerance by regulating PM Na⁺/H⁺ antiport activity and cellular redox homeostasis in Arabidopsis，Plant and Cell Physiology, 59(8):1630-1642.[第一作者/通讯作者]

10、Wenrong Tan^(#), Dawei Zhang^(#)(*), Huapeng Zhou^(#), Ting Zheng, Yanhai Yin, Honghui Lin^(*).(2018). Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genetics, 14(4):1-27.[第一作者]

9、Erbao Zhan^(#), Huapeng Zhou^(#)(*), Sha Li, Lei Liu, Tinghong Tan, Honghui Lin^(*). (2017). OTS1-dependent deSUMOylation increases tolerance to high copper levels in Arabidopsis. Journal of Integrative Plant Biology, 60(4):310-322.[第一作者/通讯作者]

8、Tinghong Tan^(#), Yanni Sun^(#), Shishuai Luo, Chao Zhang, Huapeng Zhou^(*), Honghui Lin^(*). (2017). Efficient modulation of photosynthetic apparatus confers desiccation tolerance in the resurrection plant Boea hygrometrica. Plant and Cell Physiology, 58(11):1976-1990.[通讯作者]

7、Tinghong Tan, Yanni Sun, Xingji Peng, Guochun Wu, Fang Bao, Yikun He, Huapeng Zhou^(*), Honghui Lin^(*). (2017). ABSCISIC ACID INSENSITIVE3 is involved in cold response and freezing tolerance regulation in Physcomitrella patens. Frontiers in Plant Science, doi: 10.3389/fpls.2017.01599.[通讯作者]

6、Huapeng Zhou^(*), Jinfeng Zhao, Jingqing Cai, Patil Suyash B. (2017). UBIQUITIN-SPECIFIC PROTEASES function in plant development and stress responses. Plant Molecular Biology, 94(6):565-576.[第一作者/通讯作者]

5、Tinghong Tan, Jingqing Cai, Erbao Zhan, Yongqing Yang, Jinfeng Zhao, Yan Guo, Huapeng Zhou^(*). (2016). Stability and localization of 14-3-3 proteins are involved in salt tolerance in Arabidopsis. Plant Molecular Biology, 92(3): 391-400.[通讯作者]

4、Jinfeng Zhao^(#), Huapeng Zhou^(#), Ming Zhang, Yanan Gao, Long Li, Ying Gao, Ming Li, Yuhong Yang, Yan Guo, Xueyong Li^(*). (2016). Ubiquitin-specific protease24 negatively regulates abscisic acid signaling in Arabidopsis thaliana. Plant Cell and Environment, 39(2):427-440.[第一作者]

3、Huapeng Zhou, Huixin Lin, She Chen, Katia Becker, Yongqing Yang, Jinfeng Zhao, Jörg Kudla, Karen S. Schumaker, Yan Guo^(*). (2014). Inhibition of the Arabidopsis salt overly sensitive pathway by 14-3-3 proteins. Plant Cell, 26(3):1166-1182.[第一作者]

2、Jinfeng Zhao, Huapeng Zhou, Xueyong Li. (2013). UBIQUITIN-SPECIFIC PROTEASE16 interacts with a HEAVY METAL ASSOCIATED ISOPRENYLATED PLANT PROTEIN27 and modulates cadmium tolerance. Plant Signaling & Behavior, 8(10). doi.org/10.4161/psb.25680

1、Huapeng Zhou^(#), Jinfeng Zhao(#), Yongqing Yang, Changxi Chen, Yanfen Liu, Xuehua Jin, Limei Chen, Xingwang Deng, Karen S. Schumaker, Yan Guo^(*). (2012). Ubiquitin-specific protease16 modulates salt tolerance in Arabidopsis by regulating Na⁺/H⁺ antiport activity and serine hydroxymethyltransferase stability. Plant Cell, 24(12):5106-5122.[第一作者]