张修月：博士，教授，博士生导师
联系方式：zhangxiuyue@scu.edu.cn
学习工作简历：
1985.09-1989.07 重庆师范大学生物系 大学学习，获学士学位
1989.07-1992.09 渠县琅琊中学，教师
1992.10-2002.08 攀钢（集团）公司教育处，教师
2002.09-2005.07 西南大学生命科学学院 硕士研究生学习，获硕士学位
2005.09-2008.06 四川大学生命科学学院 博士研究生学习，获博士学位
2008年07-至今 四川大学生命科学学院从事教学科研工作
主讲课程：
进化生物学（Evolutionary Biology）
动物学（Zoology）
动物生物学大实验（Zoology Experiment）
保护生物学（Conservation Biology）
主要研究领域：
动物资源保护与利用、保护遗传学、保护基因组学
主要科研项目：
大熊猫响应犬瘟热疫苗免疫相关通路表观遗传调控研究（国家自然科学基金，32070529），主持
大熊猫食物消化与代谢相关通路甲基化修饰研究（国家自然科学基金，31770574），主持；
基于血液转录组的大熊猫免疫相关基因表达谱研究（国家自然科学基金，31570534），主持；
大熊猫消化代谢相关基因对特殊食性营养利用的适应性表达及其调控研究（四川省自然科学基金项目，2022NSFSC0121），主持
动物药大品种康复新液关键质量属性制剂传递规律及动态质控模式研究（国家自然科学基金区域创新发展联合基金重点项目，U21A20409），参加，校内主持
野生动物疫病监测和预警系统维护（国家林业局项目，2130211），主持
大熊猫、林麝主要疾病检测、行为发育及干细胞资源库的建立（973项目子课题，2012CB722207），参加，校内主持；
大熊猫血液转录组学研究（成都大熊猫繁育研究基金，12H0883），主持
基于血液转录组的近亲繁殖小熊猫免疫相关基因表达谱研究（成都大熊猫繁育研究基金，CPF2017-22），主持；
中药大产品康复新液系列衍生品综合开发研究（四川省科技厅2017KJTT00068-2017S），参加校内主持；
藏酋猴微卫星分子标记的分离及其在圈养种群遗传管理中的应用（成都大熊猫繁育研究基金），主持；
保护区重点物种遗传样品采集与鉴定（彭州市规划和自然资源局项目），主持；
美洲大蠊种源遗传质量检测（四川好医生攀西药业有限责任公司项目），主持；
硬骨鱼类性别决定和分化的分子机制研究（重庆市重点实验室专项经费开放课题），主持
主要研究论文
Shen HB, Li CW, He M, Huang Y, Wang J, Luo J, Wang ML, Yue BS, Zhang XY*, 2022. Whole blood transcriptome profiling identifies candidate genes associated with alopecia in male giant pandas (Ailuropoda melanoleuca). BMC Genomics, 23: 297.
Yuan Y, Yang XT, Zeng QL, Li HY, Fu RY, Du LM, Liu W, Zhang YM, Chu YW, Zhang XY*, Zhao KL*, 2022. Dimetridazole and Ribavirin to disarm Pseudomonas aeruginosa virulence by targeting the quorum sensing system. Frontiers in Microbiology, 13: 978502.
Yan L, Hou ZZ, Ma JN, Wang HM, Gao J, Zeng CJ, Chen Q, Yue BS, Zhang XY*, 2022. Complete mitochondrial genome of Episymploce splendens (Blattodea: Ectobiidae): A large intergenic spacer and lacking of two tRNA genes. PLOS ONE, 17(6): e0268064.
Luo J, Zhang L, Shen FJ, Luo L, Chen L, Fan ZX, Hou R, Yue BS, Zhang XY*, 2022. Blood transcriptome analysis revealing aging gene expression profiles in red Panda. PeerJ, 10: e13743.
Yang M, Huang Y, Wu HL, Li CW, Ling SS, Sun J, Shen HB, Yue BS, Zhang XY*, 2022. Blood transcriptome analysis revealed the immune changes and immunological adaptation of wildness training giant pandas. Molecular Genetics and Genomics, 297(1): 227-239.
Jie XD, Wu HL, Yang M, He M, Zhao GQ, Ling SS, Huang Y, Yue BS, Yang N* and Zhang XY*, 2022. Whole genome bisulfite sequencing reveals DNA methylation roles in the adaptive response of wildness training giant pandas to wild environment. Frontiers in Genetics, 13: 995700.
Ma JN, Zhang L, Huang Y, Shen FJ, Wu HL, Yang ZY, Hou R, Song ZB, Yue BS, Zhang XY*, 2022. Epigenomic profiling indicates a role for DNA methylation in the postnatal liver and pancreas development of giant pandas. Genomics, 114: 110342.
Li L, Shen, FJ Jie XD, Zhang L, Yan GQ, Wu HL, Huang Y, Hou R, Yue BS, Zhang XY*, 2022. Comparative Transcriptomics and Methylomics Reveal Adaptive Responses of Digestive and Metabolic Genes to Dietary Shift in Giant and Red Pandas. Genes, 13: 1446.
Chen Q, Zhao K, Li HY, Liu KH, Li J, Chu YW, Prithiviraj B, Yue BS, Zhang XY*, 2022. Antibacterial and anti-virulence effects of furazolidone on Trueperella pyogenes and Pseudomonas aeruginosa. BMC Veterinary Research, 18: 114.
Cheng ML, Xie DX, Price M, Zhou C, Zhang XY*, 2022. Comparative analysis of microsatellites in coding regions provides insights into the adaptability of the giant panda, polar bear and brown bear. Genetica, 150(6): 355-366.
Sun J, Shen FJ, Zhang L, Luo L, Fan ZX, Rong Hou, Yue BS, ZhangXY*, 2021. Changes in the micro-RNA profile of the giant panda after canine distemper vaccination and the integrated analysis of micro-RNA-Messenger RNA. DNA and Cell Biology, 40: 595-605.
Shen HB, Li CW, He M, Huang Y, Wang J, Wang ML, Yue BS, Zhang XY*, 2021.Immune profiles of male giant panda (Ailuropoda melanoleuca) during the breeding season. BMC Genomics, 22: 143.
Geng Y, Shen FJ, Wu W, Zhang L, Luo L, Fan ZX, Hou R, Yue BS, Zhang XY*, 2020. First demonstration of giant panda's immune response to canine distemper vaccine. Developmental and Comparative Immunology, 102: 103489.
Wu W, Wu HL, He M, Zhang L, Huang Y, Geng Y, Liu JH, Wang Q, Fan ZX, Hou R, Yue BS, Zhang XY*, 2020. Transcriptome analyses provide insights into maternal immune changes at several critical phases of giant panda reproduction. Developmental and Comparative Immunology, 110: 103699.
Zhao KL, Li WJ, Li J, ..., Zhang XY*, Zhou XK*, 2019. TesG is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection. Nature Microbiology, 4: 459-469.
Jing J, Sun XH, Zhou C, Zhang YF, Shen YM, Zeng XM, Yue BS, Zhang XY*, 2019. Cloning, Expression and Effects of P. americana Thymosin on Wound Healing. International journal of Molecular Sciences, 20: 4932.
Ma JN, Liu JH, Shen YM, Fan ZX, Yue BS, Zhang XY*, 2019. Population genetic structure and intraspecific genetic distance of Periplaneta americana (Blattodea: Blattidae) based on mitochondrial and nuclear DNA markers. Ecology and Evolution, 1-12.
Ren JY, Shen FJ, Zhang L, Sun J, Yang MY, Yang M, Hou R, Yue BS, Zhang XY*, 2019. Single-base-resolution methylome of giant panda’s brain, liver and pancreatic tissue. Peer J, 7: e7847.
Du LM, Liu Q, Shen FJ, Fan ZX, Hou R, Yue BS, Zhang XY*, 2019. Transcriptome analysisrevealsimmune‐related gene expression changes with age in giant panda (Ailuropoda melanoleuca) blood. Aging-US, 11(1): 249-262.
Cheng ML, Ren JY, Shen FJ, Huang Y, Fan ZX, Price M, Yue BS, Zhang XY*, 2019. Genome-wide investigation of microsatellite polymorphism in coding region of the giant panda (Ailuropoda melanoleuca) genome: a resource for study of phenotype diversity and abnormal traits. Mammal Research, 64:353-363.
Ma JN, Du C, Zhou C, Sheng YM, Fan ZX, Yue BS, Zhang XY*, 2017. Complete mitochondrial genomes of two blattid cockroaches, Periplaneta australasiae and Neostylopyga rhombifolia, and phylogenetic relationships within the Blattaria. PLoS ONE, 12(5): e0177162.
Yan CC, Mou BQ, Meng Y, Tu FY, Zhenxin Fan ZX, Price M, Yue BS, Zhang XY*, 2017. A novel mitochondrial genome of Arborophila and new insight into Arborophila evolutionary history. PLoS ONE, 12(7): e01816493.
Zhao KL, Zhou XK, Li WJ, Zhang XY*, Yue BS*, 2016. Nutrient reduction induced stringent responses promote bacterial quorum-sensing divergence for population fitness. Scientific Reports, 6: 34925.
Song XH, Shen FJ, Huang J, Huang Y, Du LM, Wang CD, Fan ZX, Hou R, Yue BS, Zhang XY*, 2016. Transcriptome-derived tetranucleotide microsatellites and their associated genes from the giant panda (Ailuropoda melanoleuca). Journal of Heredity, 107(5): 423-30.
Du LM, Li WJ, Fan ZX, Shen FJ, Yang MY, Wang ZL, Jian ZY, Hou R, Yue BS, Zhang XY*, 2015. First insights into the giant panda (Ailuropoda melanoleuca) blood transcriptome: a resource for novel gene loci and immunogenetics. Molecular Ecology Resources, 15: 1001-1013.
Huang J, Li YZ, Du LM, Yang B, Shen FJ, Zhang HM, Zhang ZH, Zhang XY*, Yue BS*, 2015. Genome-wide survey and analysis of microsatellites in giant panda (Ailuropoda melanoleuca), with a focus on the applications of a novel microsatellite marker system. BMC Genomics, 16: 61.
Yang MY, Du LM, Li WJ, Shen FJ, Fan ZX, Jian ZY, Hou R, Shen YM, Yue BS, Zhang XY*, 2015. Profile of microRNA in giant panda blood: a resource for immune-related and novel microRNAs. PLOS one, e0143242.
Yue H, Yan CC, Tu F, Yang CZ, Ma WQ, Fan ZX, Song ZB, Owens J, Liu SY*, Zhang XY*, 2015. Two novel mitogenomes of Dipodidae species and phylogeny of Rodentia inferred from the complete mitogenomes. Biochemical Systematics and Ecology, 60: 123-130.
Tu FY, Liu SY, Liu Y, Sun ZY, Yin YH, Yan CC, Lu L, Yue BS, Zhang XY*, 2014. Complete mitogenome of Chinese shrew mole Uropsilus soricipes (Milne Edwards, 1871) (Mammalia: Talpidae) and genetic structure of the species in the Jiajin Mountains (China). Journal of Natural History, 48(23-24): 1467-1483.
Liu FW, Ma LL, Yng CZ, Tu FY, Xu Y, Ran JH, Yue BS, Zhang XY*, 2014. Taxonomic Status ofTetraophasis obscurusandTetraophasis szechenyii(Aves: Galliformes: Phasianidae) Based on the Complete Mitochondrial Genome. Zoological Science, 31(3): 160-167.
Huang T, Yan CC, Tan Z, Tu FY, Yue B, Zhang XY*, 2014.Complete mitochondrial genome sequence ofNectogale elegans. Mitochondrial DNA, 25(4): 253-254.
Zhao KL, Tian YQ,Yue BS, Wang HN, Zhang XY*, 2013. Virulence determinants and biofilm production among Trueperella pyogenes recovered from abscesses of captive forest musk deer. Arch Microbiol, 195: 203-209.
Yang CZ, Hao HB, Liu SY, Liu Y, Yue BS, Zhang XY*, 2012. Complete mitochondrial genome of the Chinese oriental vole Eothenomys chinensis (Rodentia: Arvicolinae). Mitochondrial DNA, 23(2):131-3.
Yue H, Fan ZX, Liu SY, Liu Y, Song ZB, Zhang XY*, 2012. A Mitogenome of the Chevrier’s Field Mouse (Apodemus Chevrieri ) and Genetic Variations Inferred from the Cytochrome b Gene. DNA and Cell Biology, 31(4): 460-9.
Jia XD, Yang B, Yue BS, Yin HL, Wang HX, Zhang XY*, 2011. Isolation and Characterization of Twenty_One Polymorphic Microsatellite Loci in the Tibetan Macaque (Macaca thibetana). Russian Journal of Genetics, 47(7): 884-887.
Chen WC, Liu SY, Liu Y, Hao HB, Zeng B, Chen SD, Peng HY, Yue BS, Zhang XY*, 2010. Phylogeography of the Large White-bellied Rat Niviventer excelsior Suggests the Influence of Pleistocene Glaciations in the Hengduan Mountains. Zoological science, 27: 487-493.
Zhang XY, Yue BS, Jiang WX, Song ZB, 2009. The complete mitochondrial genome of rock carp, Procypris rabaudi (Tchang), with the phylogenetic relationship in Cyprinidae. Molecular Biology Reports, 36: 981-991.
Zhang XY, He CL, Song ZB, 2009. Threatened fishes of the world: Zacco chengtui Kimura 1934 (Cyprinidae). Environmental Biology of Fishes, 84: 27-28.
Yue H, Yuan H, Zhang XY*, 2009. Fifteen novel polymorphic microsatellites in rock carp, Procypris rabaudi (Tchang), an endemic fish species in the upper reaches of the Yangtze River drainage. Conservation Genetics, 10: 539-542.
Zhang XY, Yue BS, Song ZB, 2008. Isolation and characterization of nine polymorphic microsatellite loci in rock carp, Procypris rabaudi (Tchang). Molecular Ecology Resources, 8: 123-125.
