邓星光,副教授
联系方式:xgdeng@scu.edu.cn
联系地址:四川省成都市一环路南一段24号,四川大学生命科学学院B407(610064)
个人主页:https://orcid.org/0000-0003-4538-2113
学习和工作经历:
2018.07-至今:四川大学,特聘副研究员,副教授
2016.01-2018.06:加州大学戴维斯分校,植物生物学,博士联合培养
2011.09-2018.06:四川大学,植物学,硕士,博士
2007.09-2011.06:济南大学,生物技术,学士
研究方向:
主要研究方向为植物细胞骨架与细胞分裂。以模式植物拟南芥为研究对象,采用细胞生物学、分子遗传学和蛋白质组学等手段,研究植物细胞分裂与发育的分子机制,解析植物细胞分裂过程中细胞骨架动态变化特征及其调控机制。重点关注有丝分裂过程中纺锤体组装、纺锤体微管与染色体连接、以及染色体整列与分离等环节的调控机制,并探讨细胞骨架在植物生长发育以及与环境互作过程中的生物学功能和作用机理。
科研项目:
国家自然科学基金面上项目,32270354,2023-2026
国家自然科学基金青年项目,31900163,2020-2022
四川省自然科学基金青年项目,22NSFSC1589,2022-2023
代表性论文(#第一作者,*通讯作者):
Xingguang Deng#,*, Yu Xiao#, Xiaoya Tang, Bo Liu*, Honghui Lin*. Arabidopsis α-Aurora kinase plays a role in cytokinesis through regulating MAP65-3 association with microtubules at phragmoplast midzone. Nature Communications. 2024, 15(1): 3779. (Nature Plants专文评述: https://doi.org/10.1038/s41477-024-01731-x)
Xingguang Deng, Felicia Lei Peng, Xiaoya Tang, Yuh-Ru Julie Lee, Honghui Lin*, Bo Liu*. The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling. PNAS. 2024, 121(12): e2322677121.
Xingguang Deng#,*, Ying He#, Xiaoya Tang#, Xianghong Liu, Yuh-Ru Julie Lee, Bo Liu*, Honghui Lin*. A coadapted KNL1 and spindle assembly checkpoint axis orchestrates precise mitosis in Arabidopsis. PNAS. 2024, 121(2): e2316583121.
Joanna Boruc#, Xingguang Deng#, Evelien Mylle, Nienke Besbrugge, Matthias Van Durme, Dmitri Demidov, Eva Dvořák Tomaštíková, Tong-Reen Connie Tan, Michaël Vandorpe, Dominique Eeckhout, Tom Beeckman, Moritz K Nowack, Geert De Jaeger, Honghui Lin, Bo Liu*, Daniël Van Damme*. TPX2-LIKE PROTEIN3 Is the Primary Activator of α-Aurora Kinases and Is Essential for Embryogenesis. Plant Physiology. 2019, 180:1389–1405.
Hongchang Zhang #, Xingguang Deng#, Baojuan Sun, Sonny Lee Van, Zhensheng Kang, Honghui Lin, Yuh-Ru Julie Lee*, Bo Liu*. Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis. Nature Plants. 2018, 4(7):485–494.
Xingguang Deng#, Tong Zhu#, Lijuan Zou, Xueying Han, Xue Zhou, Dehui Xi, Dawei Zhang*, Honghui Lin*. Orchestration of hydrogen peroxide and nitric oxide in brassinosteroid‐mediated systemic virus resistance in Nicotiana benthamiana. Plant Journal. 2016, 85(4): 478–493.
Xingguang Deng#, Tong Zhu #, Dawei Zhang*, Honghui Lin*. The alternative respiratory pathway is involved in brassinosteroid-induced environmental stress tolerance in Nicotiana benthamiana. Journal of Experimental Botany. 2015, 66(20): 6219–6232.