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李 娟
作者: user -- 发布时间:2016/6/10 20:34:16

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李娟,博士,教授,硕士生导师

联系电话:028-85415025

电子邮件:lijuanscuhk@163.com


学习与工作经历:


 1990-1994:四川大学,理学学士
 1994-1997:四川大学,理学硕士
 1997-1999:成都生物制品研究所,实习研究员
 1999-2003:香港大学动物学系,理学博士
 2004-2006:香港大学动物学系, 博士后
 2006-现在:四川大学生命科学学院讲师,副教授,教授


主要研究内容:

1,家鸡卵泡发育进程中重要基因功能鉴定与表达调控机制解析

2,肠道微生物代谢产物对动物生长发育的影响

 

项目支持:

国家自然科学基金;四川省应用基础研究基金;成都市应用基础研究基金



主要研究论文:

1  Mo C, Cai G, Huang L, Deng Q, Lin D, Cui L, Wang Y, Li Juan* 2015Corticotropin-releasing Hormone (CRH) Stimulates Cocaine- and amphetamine-regulated Transcript Gene (CART1) Expression through CRH Type 1 Receptor (CRHR1) in Chicken Anterior Pituitary. Mol Cell Endocrinol. 417166-177 (*通讯作者)

2  Cai G, Mo C, Huang L, Li Juan*, Wang Y*2015Characterization of the Two CART Genes (CART1 and CART2) in Chickens (Gallus gallus). PLoS One. 18;10(5):e0127107. (*通讯作者)

3   Li  X, Fang W, Hu Y, Wang Y, Li Juan* 2015Characterization of fibronectin type III domain-containing protein 5 (FNDC5) gene in chickens: Cloning, tissue expression, and regulation of its expression in the muscle by fasting and cold exposure.Gene. 10;570(2):221-9. (*通讯作者)

4  Zhang J, Cheng S, Wang Y, Yu X, Li Juan* (2014) Identification and characterization of the free fatty acid receptor 2 (FFA2) and a novel functional FFA2-like receptor (FFA2L) for short-chain fatty acids in pigs: Evidence for the existence of a duplicated FFA2 gene (FFA2L) in some mammalian species. Domestic Animal Endocrinology 47:108-118 (*通讯作者)

5  Mo C, Zhong Y, Wang Y, Yan Z,  Li Juan*  (2014)  Characterization of glucagon-like peptide 2 receptor (GLP2R) gene in chickens: functional analysis, tissue distribution, and developmental expression profile of GLP2R in embryonic intestine. Domestic Animal Endocrinology 48:1-6 (*通讯作者)

6   He X, Meng F, Wang Y, Li Juan*  (2014)  Molecular Cloning and Characterization of Two Pig Vasoactive Intestinal Polypeptide Receptors (VPAC1-R and VPAC2-R). DNA Cell Biol. 33:259-270 (*通讯作者)

7   Li Juan*, Meng F, Song C, Wang Y, Leung FC* (2012) Characterization of chicken visfatin gene: cDNA cloning, Tissue expression, and promoter analysis. Poultry Science 91: 2885-94 (*通讯作者)

8  Huang G, Li Juan*, Fu H, Yan Z, Bu G, He X, Wang Y* (2012) Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants.  Domestic Animal Endocrinology 43: 1-15 (*通讯作者)

9  Wang Y, Huang G,  Li Juan, Meng F, He X. Leung F.C* (2012) Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene.  Molecular and Cellular Endocrinology, 348: 270-280 (*通讯作者)

10  Yao Meng, Shuangfeng Liu, Juan Li, Yanfa Meng, Xiaojun Zhao* (2012) Preparation of an antitumor and antivirus agent: chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol  Int J Nanomedicine. 7: 3133–3142. (*通讯作者)

11.  Wang Y*, Huang G, Li Juan, Meng F, He X. Leung F.C* (2012) Characterization of Chicken Secretin (SCT) and Secretin Receptor (SCTR) Genes: A Novel Secretin-like Peptide (SCT-LP) and Secretin Encoded in a Single Gene. Molecular and Cellular Endocrinology 348: 270-280 (*通讯作者).

12  Wang Y, Li Juan, Kwok AHY, Ge W & Lueng FC* (2010) A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: Cloning and Characterization of its tissue expression. General and Comparative endocrinology 166: 200-210. (*通讯作者)

13  Wang Y, Li Juan, C. Wang CY,  Kwok AHY, Zhang X & Leung FC (2010) Characterization of the receptors for chicken GHRH and GHRH-related peptides: Identification of a novel receptor for GHRH and the receptor for GHRH-LP (PRP). Domestic Animal Endocrinology 38: 13-31. (*通讯作者)

14  Wang J, Wang Y, Li X,  Li Juan* and Leung FC* (2008) Cloning, tissue distribution and functional characterization of chicken glucagon receptor. Poultry Science 872678-2688 (*通讯作者)

15  Wang Y, Li Juan, Wang CY, Kwok AHY, Leung FC* (2007) Identification of the endogenous ligands for chicken growth hormone-releasing hormone (GHRH) receptor. Evidence for a separate gene encoding GHRH in submammalian vertebrates. Endocrinology 148: 2405-2416 (*通讯作者)

16  Wang Y, Li JuanWang CY, Kwok AHY, Leung FC* (2007) Epidermal growth factor receptor (EGFR) ligand in the chicken ovary: I) Evidence for heparin binding epidermal growth factor-like growth factor (HB-EGF) as a potential oocyte-derived factor to control granulosa cell proliferation and HB-EGF and Kit ligand expression. Endocrinology 148: 3426 – 3440. (*通讯作者)

17  Wang Y, Wang Z, Li Juan, Wang Y*, Leung FC* (2007) A database for chicken full-length cDNAs. Physiological Genomics 28:141-5, (*通讯作者)

18  Li Juan, Wang X, and Leung FC* (2007) The intragenomic polymorphism of a partially inverted repeat (PIR) in Gallus gallus domesticus, potential role of inverted repeats in satellite DNAs evolution. Gene 387:118-125. (*通讯作者)

19  Li Juan and Leung FC * (2006) A CR1 element is embedded in a novel tandem repeat (HinfI repeat) within the chicken genome. Genome 49:97-103. (*通讯作者)

20  Wang CY, Wang Y, Li Juan and Leung FC* (2006) Expression profiles of growth hormone-releasing hormone and growth hormone-releasing hormone receptor during chicken embryonic pituitary development. Poultry Science 85:569-576. (*通讯作者)

21   Wang X, Li Juan and Leung FC* (2002) Partially inverted tandem repeat isolated from pericentric region of chicken chromosome 8. Chromosome Res 10:73-82. (*通讯作者)

22   Li Juan, Wang X and Leung FC* (2002) Partially inverted repetitive satellite DNA: A potential indicator for genetic homozygosity in chicken. 7th World Congress on Genetics Applied to Livestock Production 33:113-115.

 

 

 

获 奖

第七届大学生《挑战杯》课外学术活动竞赛:代表香港大学获特等奖

2008,2011,2012年度四川大学青年骨干教师奖

《精品开放课程建设突出贡献奖》(细胞生物学课程组,排名第三)

 

 


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